Altered Phys

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Submitted By Syed2818
Words 5199
Pages 21
Altered Phys. Notes
Lecture 1: (September 17, 2015)
What does physiology mean? * Normal function of a living thing, human cell, tissue, organ , system
What is Pathophysiology? * Abnormal function caused by an adverse event/stimulus * The event can be mechanical/chemical/radiation/etc. * It has a negative impact on function
How relevant is A&P to Patho? * Pretty relevant * You know when something is wrong with the human body if you know how it functions when its healthy * You need to know what’s normal to appreciate what’s different
Cell and tissue biology * If you can understand what is happening in a cell, you can see what is happening in a tissue, (tissue is group of cells performing a similar function) * Injuries can be caused by chemical, intentional or unintentional, etc.
Sub-lethal (reversible), or lethal (irreversible) * Cellular aging is a normal part of cell life
Structural and functional changes leading to cell death or decreased capacity to heal * Different cells age at different rates * Skin cells get replaced every day, red blood cells get replaced every 4 months * There are 5 million blood cells travelling in the human body at a time
Adaptation: how a cell responds to stimulus (ex. Pregnancy), to escape and protect themselves from injury
Normal cells meet injury it could do one of two things * It could say, I’m going to change myself so I can stay healthy adaptation * If the adaptation doesn’t work or unsuccessful, then the cell becomes injured * When cell goes from normal to adapted, what happens is that these states are reversible
Atrophy
* Once a cell reached a certain age, the cell will die * Once a cell decreases in size the organ will also decrease (muscle, heart, brain) * Your uterus lining has atrophied so that’s the reason why women have menstruation,…...

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