Sulfonamides

In: Science

Submitted By Marlu
Words 1851
Pages 8
SULFONAMIDES

Abstract
Sulfonamides are among one of the oldest drugs to be used as antibiotics. They were invented in 1930's. Nowadays doctors prefer to prescribe them as the traditional drug of choice for urinary tract infections and sexually transmitted diseases. Currently, the new development of antibiotics to combat illnesses caused by bacterial resistant strains and have limited the usefulness of Sulfa medications.

Objectives
Upon successful completion of this presentation you should be able to:
• Understand and communicate your knowledge of Sulfonamides mode of action and bacterial resistance
• Identify and understand the contra indications, common signs and symptoms of allergic reactions to Sulfonamides.
• Identify 3 common trade names for sulfonamides and select indication for use between different patient population.

Type and class of Pathogen
Sulfonamides have been in use since the 1930's , these drugs are effective against both gram- negative and gram - positive bacteria. Sulfonamides are know as broad spectrum antimicrobial drugs; they are effective against a wide variety of microorganisms most Enterobacteriaceae, Chlamydia trachomatis, Nisseria, Haemophilus influenzae,, Norcardia, E.Coli , P. mirabilis some staphylococci, and many streptococci (with exception of Enterococcus faecalis). They are used for treatment of Protozoan such as Toxoplasma gondii, and mycobacterial. Sulfonamides are use for treatment and prophylaxis of Pneumocytis carinii and Shigella small bowel infections.

Mode of Action Sulfonamides are bacteriostatic anti-invectives that "inhibit bacteria" growth but do not destroy it (Lilley, Collins, Harrington & Snyder, 2011). By preventing the bacterial synthesis of a…...

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